Here are some of the biggest movers in midday trading. Moderna – Shares of the biotech giant climbed 5% after the company gave upbeat guidance for full-year revenue. Moderna expects revenue growth of up to 10% from 2025’s levels, beating the FactSet consensus call for a 5.9% increase. Fourth-quarter losses came in at $2.11 per share, narrower than the $2.54 loss per share predicted by analysts. Maplebear – Shares surged about 9% after the parent company of grocery delivery platform Instacart, issued an optimistic forecast for its current quarter. Instacart expects gross transaction value in the range of about $10.13 billion to $10.28 billion, versus a $9.97 billion StreetAccount estimate. The company also see its adjusted EBITDA coming in between $280 million and $290 million, surpassing the $277.3 million forecast. Maplebear also posted a revenue beat for its last quarter. Constellation Brands — The alcohol producer and marketer fell around 5% after the company announced Nicholas Fink will replace Bill Newlands as CEO on April 13. Fink was previously CEO of Fortune Brands Innovations, a home and security products manufacturer. Wendy’s – The fast-food chain saw shares jump 4% after fourth-quarter results outpaced expectations. Wendy’s reported adjusted earnings of 16 cents per share on revenue of $543 million, while the FactSet consensus sought 14 cents per share in earnings and $537.2 million in revenue. Dexcom – The maker of glucose monitoring systems jumped nearly 9%. Adjusted earnings in the fourth quarter came in at 68 cents a share, surpassing the FactSet consensus of 65 cents per share. Dexcom stuck with its 2026 guidance, however, calling for revenue in a range of $5.16 billion to $5.25 billion. Vertex Pharmaceuticals – The biotech play saw shares climb 6%. Fourth-quarter revenue came in at $3.19 billion, narrowly beating the FactSet consensus forecast for $3.18 billion. Norwegian Cruise Line – Shares of the cruise operator dropped 5%. The company named director John Chidsey as its CEO, effective immediately. He succeeds Harry Sommer, who stepped down from the helm, as well as from his post as director. DraftKings — Shares fell about 13% after the sports betting operator’s 2026 revenue forecast disappointed. In the fourth quarter, DraftKings earned 25 cents per share on revenue of $1.99 billion. That was better than the LSEG estimate of 15 cents per share in earnings and $1.98 billion in revenue. However, the company expects revenue this year to be between $6.5 billion and $6.9 billion, far below the consensus estimate of $7.31 billion. Roku — Shares rose almost 8%. The company issued better-than-expected forward guidance for 2026. The TV streaming platform said it expects to notch $635 million in adjusted EBITDA and $5.5 billion in revenue by the end of this year, beating the FactSet consensus forecast of $579.7 million in adjusted EBITDA and $5.34 billion in revenue. Rivian Automotive — The electric truck manufacturer surged 26%. The company said it sees 2026 vehicle deliveries ranging from 62,000 to 67,000 units , which would be higher by 47% to 59% compared to 2025. Fourth-quarter adjusted losses came in at 54 cents per share, narrower than the LSEG consensus for a loss of 68 cents per share. Revenue of $1.29 billion topped the estimate of $1.26 billion. Applied Materials — The California-based semiconductor equipment company jumped 9% on the back of blowout earnings results. Applied Materials reported adjusted earnings of $2.38 per share on revenue of $7.01 billion, while analysts polled by LSEG expected earnings of $2.20 per share on revenue of $6.87 billion. Expedia Group — Shares of the online travel agency slid more than 7% after Expedia identified “emerging AI-powered platforms” in its earnings presentation as a potential risk, even as it posted fourth quarter results that beat expectations. Expedia earned $3.78 per share, on an adjusted basis, on revenues of $3.55 billion. That was better than the earnings of $3.36 per share on revenues of $3.42 billion expected by analysts polled by LSEG. Coinbase — Shares of the crypto company rose 17%. Coinbase said that its total trading volume in 2025 hit $5.2 trillion, up 156% year over year. The firm also reported that its subscription and services revenue rose to $2.8 billion in 2025, up from $2.3 billion in the year prior. That’s despite Coinbase falling short of the Street’s expectations on revenue for the fourth quarter. Pinterest — Shares of the social media company plunged 18%. Pinterest posted disappointing fourth-quarter results and gave weak guidance for first-quarter sales. For its previous period, Pinterest earned 67 cents per share, excluding items, while analysts polled by LSEG expected 69 cents per share. Fourth-quarter revenue of $1.32 billion came out slightly lower than the $1.33 billion expected in the LSEG consensus. — CNBC’s Sarah Min, Davis Giangiulio and Lisa Kailai Han contributed reporting.