UPS plane crashes after taking off from Louisville airport

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A plume of smoke wafts over airport property after reports of a plane crash at Louisville International Airport, Tuesday, Nov. 4, 2025, in Louisville, Ky.

Jon Cherry | AP

A UPS plane crashed on Tuesday around 5:15 p.m. local time after departing from Louisville Muhammad Ali International Airport in Kentucky, the Federal Aviation Administration said.

UPS said in a statement that there were three crewmembers onboard. “At this time, we have not confirmed any injuries/casualties,” the company said.

The FAA said the plane was en route to Honolulu and that it and the National Transportation Safety Board would investigate the incident.

The Louisville Metro Police Department said on X that a shelter-in-place order had been issued for all locations within 5 miles of the airport.

Kentucky Gov. Andy Beshear said “the situation is serious” on X and that he was headed to Louisville.

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